
Thermo Fisher Scientific ERN2 Polyclonal Antibody
Mouse ERN2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. KLH 결합 합성 펩타이드로 면역화되었으며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:1,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 883–911 of the C-terminal region of mouse Ern2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2900862 |
Target Information
ERN2 (endoplasmic reticulum to nucleus signaling 2) is a serine/threonine kinase and human homolog of the yeast Ire1 gene product. It plays a role in multiple aspects of the ER stress response in mammalian cells. Unlike related proteins, this pro-apoptotic factor does not participate in the unfolded-protein response. Overexpression of ERN2 activates BiP and CHOP expression, leading to programmed cell death. Ern2 is suggested to be involved in various facets of the ER stress response in mammalian systems.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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