Thermo Fisher Scientific TCAP Polyclonal Antibody
Human TCAP 단백질에 특이적인 Rabbit Polyclonal Antibody로, Western blot 및 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 저장용액에 포함되어 안정적입니다. 근육 단백질 티틴 관련 연구용으로 사용됩니다.
- 카탈로그번호
- PA555315
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- Publications: [참고 문헌 없음]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: [참고 문헌 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TCAP. Recombinant protein control fragment (Product #RP-93427) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648303 |
Product Specific Information
Immunogen sequence:
CEVSEENCER REAFWAEWKD LTLSTRPEEG CSLHEEDTQR HETYHQQGQC QVLVQRSPWL MMRMGILGRG LPEYQ
Antigen sequence identity:
- Mouse: 89%
- Rat: 65%
Target Information
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere and serves as a scaffold for myofibrils and other muscle-related proteins.
TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and acts as a substrate of titin kinase, interactions thought to be critical to sarcomere assembly.
Mutations in the TCAP gene are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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