Thermo Fisher Scientific GPR116 Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 1:500–1:1,000
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Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.

Target Information

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors or 7TM receptors, form a superfamily of proteins involved in various stimulus-response pathways. These receptors translate extracellular signals into intracellular responses via G protein activation and respond to signaling molecules such as hormones and neurotransmitters.

GPR116 (G protein-coupled receptor 116) is a 1,346 amino acid multi-pass membrane protein containing one SEA domain, one GPS domain, and three Ig-like domains, belonging to the GPR family. It exists as a disulfide-linked homodimer at the cell surface and has multiple alternatively spliced isoforms. GPR116 is thought to play a role in regulating and maintaining proper acid-base balance within cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.