Thermo Fisher Scientific CLDN1 Monoclonal Antibody (1C5-D9)
인간 Claudin-1 단백질을 인식하는 mouse monoclonal antibody로 Western blot, IHC, ELISA, IP에 사용 가능. 고순도 affinity chromatography로 정제된 액상 형태. -20°C에서 보관하며 연구용으로만 사용.
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Thermo Fisher Scientific CLDN1 Monoclonal Antibody (1C5-D9)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 0.03 ng/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C5-D9 |
| Immunogen | CLDN1 (AAH12471.1, 1–211 a.a.) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MANAGLQLLG FILAFLGWIG AIVSTALPQW RIYSYAGDNI VTAQAMYEGL WMSCVSQSTG QIQCKVFDSL LNLSSTLQAT RALMVVGILL GVIAIFVATV GMKCMKCLED DEVQKMRMAV IGGAIFLLAG LAILVATAWY GNRIVQEFYD PMTPVNARYE FGQALFTGWA AASLCLLGGA LLCCSCPRKT TSYPTPRPYP KPAPSSGKDY V
Target Information
Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions. It acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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