Thermo Fisher Scientific Human 4-1BB Ligand (TNFSF9) Recombinant Protein, PeproTech
Recombinant Human 4-1BB Ligand (TNFSF9) 단백질로, 인간 PBMC에서 IL-8 생산을 자극하는 생물학적 활성을 가집니다. E. coli 발현 시스템에서 생산되었으며, ≥98% 순도와 낮은 endotoxin 수준을 보장합니다. 면역세포 활성화 연구 및 기능 분석용으로 적합합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
Western Blot (WB)
- Assay-dependent
ELISA
- Assay-dependent
Functional Assay
- Assay-dependent
In vitro Assay
- Assay-dependent
View 3 publications
Miscellaneous (PubMed)
- Assay-dependent
View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Human, Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | MREGPELSPD DPAGLLDLRQ GMFAQLVAQN VLLIDGPLSW YSDPGLAGVS LTGGLSYKED TKELVVAKAG VYYVFFQLEL RRVVAGEGSG SVSLALHLQP LRSAAGAAAL ALTVDLPPAS SEARNSAFGF QGRLLHLSAG QRLGVHLHTE ARARHAWQLT QGATVLGLFR VTPEIPAGLP SPRSE |
| Molecular Weight | 19.5 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% (SDS-PAGE, HPLC) |
| Endotoxin Concentration | <1 EU/µg |
| Activity | Dose-dependent stimulation of IL-8 production by human PBMC (ED50: 5–10 ng/ml). Results may vary with PBMC donors. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human 4-1BBL is a soluble 19.5 kDa protein consisting of 185 amino acid residues.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
CD137 ligand (CD137L) is a type II membrane protein and a member of the TNF superfamily. It acts as a co-stimulatory molecule expressed on antigen-presenting cells such as dendritic cells, monocytes/macrophages, and B cells, and is upregulated upon activation.
Its receptor, CD137/4-1BB, is found on various cells including inflamed endothelial cells, where interaction with CD137L enhances monocyte extravasation. Activated T cells express CD137, and engagement with CD137L promotes T cell proliferation, IL-2 secretion, survival, and cytotoxic activity.
CD137L is also expressed in most B-cell lymphomas (mantle cell, follicular, diffuse large B-cell) but absent in Hodgkin and T-cell lymphomas. It is also found in carcinoma cell lines, suggesting involvement in T cell–tumor cell interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Human BAFF Receptor Recombinant Protein, PeproTech
138,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Human TNF-RII (soluble) Recombinant Protein, PeproTech
138,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Human 4-1BB Ligand (TNFSF9) Recombinant Protein, PeproTech
139,800원
Thermo Fisher Scientific
Thermo Fisher Scientific Human APRIL Recombinant Protein, PeproTech
138,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Human APRIL Recombinant Protein, PeproTech
4,690,100원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|