Thermo Fisher Scientific Phospho-HPRT1 (Ser110) Polyclonal Antibody
HPRT1 단백질의 Ser110 인산화 형태를 특이적으로 인식하는 폴리클로날 항체로, Western blot 및 IHC(파라핀) 실험에 적합. 인간, 생쥐, 랫트 반응성. 고순도 정제 및 안정적 PBS/glycerol 용액 형태로 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HPRT1 (Accession P00492), corresponding to amino acid residues around phosphorylated Ser110 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816770 |
Product Specific Information
Antibody detects endogenous levels of HPRT1 only when phosphorylated at Ser110.
Target Information
The protein is a transferase that catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate.
This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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