Thermo Fisher Scientific Phospho-GLI1 (Thr1074) Polyclonal Antibody

Thermo Fisher Scientific Phospho-GLI1 (Thr1074) Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:2,000

Species Reactivity

• Human
• Mouse

Host / Isotype

• Rabbit / IgG

Class

• Polyclonal

Type

• Antibody

Immunogen

A synthesized peptide derived from human GLI1 (Accession P08151), corresponding to amino acid residues around phosphorylated Thr1074.

Conjugate

• Unconjugated

Form

• Liquid

Concentration

• 1 mg/mL

Purification

• Sequential chromatography

Storage Buffer

• PBS, pH 7.4, with 50% glycerol

Contains

• 0.02% sodium azide

Storage Conditions

• −20°C

Shipping Conditions

• Wet ice

RRID

• AB_2816773

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Product Specific Information

This antibody detects endogenous levels of Gli1 only when phosphorylated at Thr1074.

Target Information

This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation.
The activity and nuclear localization of this protein are negatively regulated by p53 in an inhibitory loop.
Multiple transcript variants encoding different isoforms have been found for this gene.

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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.