Thermo Fisher Scientific COQ3 Polyclonal Antibody, MaxPab
COQ3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간 COQ3 전장 단백질을 면역원으로 사용하였으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- H00051805-B01P
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | COQ3 (AAH63463.1, 1–369 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MWSGRKLGSS GGWFLRVLGP GGCNTKAARP LISSAVYVKN QLSGTLQIKP GVFNEYRTIW FKSYRTIFSC LNRIKSFRYP WARLYSTSQT TVDSGEVKTF LALAHKWWDE QGVYAPLHSM NDLRVPFIRD NLLKTIPNHQ PGKPLLGMKI LDVGCGGGLL TEPLGRLGAS VIGIDPVDEN IKTAQCHKSF DPVLDKRIEY RVCSLEEIVE ETAETFDAVV ASEVVEHVID LETFLQCCCQ VLKPGGSLFI TTINKTQLSY ALGIVFSEQI AGIVPKGTHT WEKFVSPETL ESILESNGLS VQTVVGMLYN PFSGYWHWSE NTSLNYAAHA VKSRVQEHPA SAEFVLKGET EELQANACTN PAVHEKLKK
Target Information
Ubiquinone (Coenzyme Q, or Q) is a critical component of the electron transport pathways of both eukaryotes and prokaryotes.
This lipid consists of:
- A hydrophobic isoprenoid tail anchoring coenzyme Q to the membrane
- A quinone head group responsible for activity in the respiratory chain
The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for two steps in the biosynthetic pathway of coenzyme Q.
This enzyme methylates:
- An early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid
- The final intermediate, converting demethyl-ubiquinone to coenzyme Q
The COQ3 gene product can also methylate the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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