Thermo Fisher Scientific EMAP II Polyclonal Antibody
EMAP II 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, Flow Cytometry, Immunoprecipitation 등 다양한 응용에 적합. 고순도 Affinity chromatography로 정제되어 높은 특이성과 재현성을 제공. 연구용 전용 제품.
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- PA5102719
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human AIMP1 (Accession Q12904), amino acid residues T117–K167 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852110 |
Product Specific Information
Antibody detects endogenous levels of total AIMP1.
Target Information
The protein encoded by this gene acts as a cytokine specifically induced by apoptosis and plays a role in angiogenesis, inflammation, and wound healing. Its release sensitizes tumor-associated vasculature to tumor necrosis factor. The precursor protein corresponds to the p43 subunit of the multi-tRNA synthetase complex, modulating aminoacylation activity in normal cells. After proteolytic cleavage in tumor cells, it stimulates inflammatory responses. Multiple transcript variants encoding different isoforms have been identified, and a pseudogene is present on chromosome 20.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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