Thermo Fisher Scientific H3K14me1 Polyclonal Antibody
H3K14me1 단일메틸화 히스톤 H3를 인식하는 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합. 고순도 액상 형태로 제공되며 -20°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic methylated peptide derived from human Mono-Methyl-Histone H3 around the methylation site of Lys14 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815932 |
Product Specific Information
Antibody detects endogenous levels of Mono-Methyl-Histone H3 only when methylated at Lys14.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translationally, histones are modified in various ways to either directly change chromatin structure or enable binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the nucleosome core and can undergo several types of post-translational modification, including methylation or acetylation of lysine and arginine residues and phosphorylation of serine or threonine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-102713_H3K14me1_P68431-1_Rabbit.svg, PA5-102713_H3K14me1_Q71DI3-1_Rabbit.svg 등)
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