Thermo Fisher Scientific PSMD10 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000
• Publications: [참고문헌 링크]

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200
• Publications: [참고문헌 링크]

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total PSMD10.

Target Information

The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator.

• The 20S core consists of 4 rings (2 alpha and 2 beta rings, each with 7 subunits).
• The 19S regulator includes a base (6 ATPase and 2 non-ATPase subunits) and a lid (up to 10 non-ATPase subunits).
  Proteasomes are abundant in eukaryotic cells and cleave peptides via an ATP/ubiquitin-dependent, non-lysosomal pathway.
  The immunoproteasome plays an essential role in class I MHC peptide processing.
  This gene encodes a non-ATPase subunit of the 19S regulator, with two transcript isoforms and pseudogenes on chromosomes 3 and 20.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 없음)