Thermo Fisher Scientific H2BK23ac Recombinant Rabbit Monoclonal Antibody (RM260)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-2 µg/mL

-

Immunocytochemistry (ICC/IF)

0.5-2 µg/mL

-

ELISA (ELISA)

0.2-1 µg/mL

-

Luminex (LUM)

0.1-0.5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

RM260

Immunogen

An acetyl-peptide corresponding to Acetyl-Histone H2B (Lys23) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:H2BK23ac,uniProtId:O60814-1,ncbiNodeId:9606,antigenRange:23,antigenLength:126,antigenImageFileName:MA5-27885_H2BK23ac_O60814-1_Rabbit.svg,antigenImageFileNamePDP:MA5-27885_H2BK23ac_O60814-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:H2BK23ac,uniProtId:Q93079-1,ncbiNodeId:9606,antigenRange:23,antigenLength:126,antigenImageFileName:MA5-27885_H2BK23ac_Q93079-1_Rabbit.svg,antigenImageFileNamePDP:MA5-27885_H2BK23ac_Q93079-1_Rabbit_PDP.jpeg,sortOrder:10},{targetFamily:H2BK23ac,uniProtId:Q99877-1,ncbiNodeId:9606,antigenRange:23,antigenLength:126,antigenImageFileName:MA5-27885_H2BK23ac_Q99877-1_Rabbit.svg,antigenImageFileNamePDP:MA5-27885_H2BK23ac_Q99877-1_Rabbit_PDP.jpeg,sortOrder:11},{targetFamily:H2BK23ac,uniProtId:Q99879-1,ncbiNodeId:9606,antigenRange:23,antigenLength:126,antigenImageFileName:MA5-27885_H2BK23ac_Q99879-1_Rabbit.svg,antigenImageFileNamePDP:MA5-27885_H2BK23ac_Q99879-1_Rabbit_PDP.jpeg,sortOrder:12},{targetFamily:H2BK23ac,uniProtId:Q99880-1,ncbiNodeId:9606,antigenRange:23,antigenLength:126,antigenImageFileName:MA5-27885_H2BK23ac_Q99880-1_Rabbit.svg,antigenImageFileNamePDP:MA5-27885_H2BK23ac_Q99880-1_Rabbit_PDP.jpeg,sortOrder:13},{targetFamily:H2BK23ac,uniProtId:P06899-1,ncbiNodeId:9606,antigenRange:23,antigenLength:126,antigenImageFileName:MA5-27885_H2BK23ac_P06899-1_Rabbit.svg,antigenImageFileNamePDP:MA5-27885_H2BK23ac_P06899-1_Rabbit_PDP.jpeg,sortOrder:2},{targetFamily:H2BK23ac,uniProtId:P23527-1,ncbiNodeId:9606,antigenRange:23,antigenLength:126,antigenImageFileName:MA5-27885_H2BK23ac_P23527-1_Rabbit.svg,antigenImageFileNamePDP:MA5-27885_H2BK23ac_P23527-1_Rabbit_PDP.jpeg,sortOrder:3},{targetFamily:H2BK23ac,uniProtId:P33778-1,ncbiNodeId:9606,antigenRange:23,antigenLength:126,antigenImageFileName:MA5-27885_H2BK23ac_P33778-1_Rabbit.svg,antigenImageFileNamePDP:MA5-27885_H2BK23ac_P33778-1_Rabbit_PDP.jpeg,sortOrder:4},{targetFamily:H2BK23ac,uniProtId:P57053-1,ncbiNodeId:9606,antigenRange:23,antigenLength:126,antigenImageFileName:MA5-27885_H2BK23ac_P57053-1_Rabbit.svg,antigenImageFileNamePDP:MA5-27885_H2BK23ac_P57053-1_Rabbit_PDP.jpeg,sortOrder:5},{targetFamily:H2BK23ac,uniProtId:P62807-1,ncbiNodeId:9606,antigenRange:23,antigenLength:126,antigenImageFileName:MA5-27885_H2BK23ac_P62807-1_Rabbit.svg,antigenImageFileNamePDP:MA5-27885_H2BK23ac_P62807-1_Rabbit_PDP.jpeg,sortOrder:6},{targetFamily:H2BK23ac,uniProtId:Q16778-1,ncbiNodeId:9606,antigenRange:23,antigenLength:126,antigenImageFileName:MA5-27885_H2BK23ac_Q16778-1_Rabbit.svg,antigenImageFileNamePDP:MA5-27885_H2BK23ac_Q16778-1_Rabbit_PDP.jpeg,sortOrder:7},{targetFamily:H2BK23ac,uniProtId:Q5QNW6-1,ncbiNodeId:9606,antigenRange:23,antigenLength:126,antigenImageFileName:MA5-27885_H2BK23ac_Q5QNW6-1_Rabbit.svg,antigenImageFileNamePDP:MA5-27885_H2BK23ac_Q5QNW6-1_Rabbit_PDP.jpeg,sortOrder:8},{targetFamily:H2BK23ac,uniProtId:Q8N257-1,ncbiNodeId:9606,antigenRange:23,antigenLength:126,antigenImageFileName:MA5-27885_H2BK23ac_Q8N257-1_Rabbit.svg,antigenImageFileNamePDP:MA5-27885_H2BK23ac_Q8N257-1_Rabbit_PDP.jpeg,sortOrder:9}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2744939

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Target Information

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.