Thermo Fisher Scientific H2BK23ac Recombinant Rabbit Monoclonal Antibody (RM260)
H2BK23ac 표적에 특이적인 재조합 토끼 단클론 항체로 높은 특이성과 민감도를 제공. Western blot, ICC/IF, ELISA, Luminex 등 다양한 응용에 적합. HEK293 세포 발현 시스템으로 생산되어 로트 간 일관성 및 동물 유래 성분 무함유. 연구용으로만 사용 가능.
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Thermo Fisher Scientific H2BK23ac Recombinant Rabbit Monoclonal Antibody (RM260)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.5–2 µg/mL |
| ELISA | 0.2–1 µg/mL |
| Luminex (LUM) | 0.1–0.5 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RM260 |
| Immunogen | Acetyl-peptide corresponding to Acetyl-Histone H2B (Lys23) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2744939 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of core histones (H2A, H2B, H3, and H4). These nucleosomes compact DNA into chromatin, regulating DNA accessibility for transcription, repair, replication, and maintaining chromosomal stability.
H2B also exhibits broad antibacterial activity.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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