Thermo Fisher Scientific RGS4 Polyclonal Antibody
RGS4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot 등 연구용에 적합합니다. Human에 반응하며, 고순도 Affinity Chromatography로 정제되었습니다. PBS 및 sucrose buffer에 보관하며 -20°C에서 안정적입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human RGS4 (aa 151–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608653 |
Product Specific Information
- Peptide sequence: EAQKKIFNLM EKDSYRRFLK SRFYLDLVNP SSCGAEKQKG AKSSADCASL
- Sequence homology:
Cow: 86%
Dog: 92%
Guinea Pig: 93%
Horse: 93%
Human: 100%
Mouse: 100%
Rabbit: 86%
Rat: 100%
Sheep: 86%
Target Information
Regulator of G protein signaling (RGS) family members act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins deactivate G protein subunits of Gi alpha, Go alpha, and Gq alpha subtypes, driving them into their inactive GDP-bound forms.
Regulator of G protein signaling 4 (RGS4) belongs to this family and shares a conserved 120-amino acid RGS domain. RGS4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. It negatively regulates signaling upstream or at the level of heterotrimeric G proteins and is localized in the cytoplasm.
Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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