Thermo Fisher Scientific Human ZIP1 Synthetic Peptide
휴먼 ZIP1 단백질 아미노 말단의 16개 아미노산 서열을 기반으로 한 합성 펩타이드. ZIP1 항체 차단용으로 사용 가능. 인간 반응성, 비결합형 액상 형태. 연구용 시약으로 암 연구 및 ZIP1 기능 분석에 적합.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the amino terminus of human ZIP1.
PEP-1180 can be used as a blocking peptide with polyclonal antibody PA5-21066.
Target Information
ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters.
Zinc is an essential ion for cells and plays significant roles in growth, development, and differentiation.
ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer.
Studies show that overexpression of ZIP1 and increased intracellular zinc levels in PC-3 cells inhibit NF-kappa-B, leading to down-regulation of antiapoptotic proteins (Bcl-2, Bcl-XL, XIAP), thereby reducing malignant potential in vitro and in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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