Thermo Fisher Scientific Human TMEM59 Synthetic Peptide
인간 TMEM59의 N-말단 16개 아미노산 서열에 해당하는 합성 펩타이드로, PA5-21065 항체의 블로킹 펩타이드로 사용 가능. Alzheimer 연구 관련 APP 처리 조절 단백질 연구에 적합. 정제된 액상 형태로, PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide 포함.
- 카탈로그번호
- PEP1179
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human TMEM59 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the amino terminus of human TMEM59.
PEP-1179 can be used as a blocking peptide with polyclonal antibody PA5-21065.
Target Information
Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis.
TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP, or PRNP. It inhibits APP transport and shedding.
주의사항
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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