Thermo Fisher Scientific Human SLC39A3 Synthetic Peptide
Human SLC39A3(ZIP3) 유래 합성 펩타이드로, 항체 차단 실험용으로 사용 가능. 정제된 액상 형태이며 PBS 버퍼에 0.1% BSA 포함. 연구용으로만 사용 가능.
- 카탈로그번호
- PEP1182
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the center of human ZIP3.
PEP-1182 can be used as a blocking peptide with polyclonal antibody PA5-21068.
Target Information
The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3- mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down-regulated in human prostate adenocarcinomatous glands and may be important in the retention of zinc in the cellular compartment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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