Thermo Fisher Scientific KELL Monoclonal Antibody (BRIC203)

Applications

Flow Cytometry (Flow)

• Tested Dilution: Assay-dependent

Immunoprecipitation (IP)

• Tested Dilution: Assay-dependent

Hemagglutination Assay (HA)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• In hemagglutination tests, MA1-80068 reacts with Kp(a-b+) but not Kp(a+b-).
• This antibody agglutinates Kp(a+b-c+) and Kp(a-b-c+) erythrocytes but does not react with Ko erythrocytes.
• For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.
• Mouse anti-Human CD238 antibody, clone BRIC203, recognizes human CD238 (Kell blood group antigen Kpbc).
• Kell antigens are carried on the ~93 kDa erythrocyte membrane glycoprotein.

Target Information

The Kell gene encodes a type II transmembrane glycoprotein that represents the highly polymorphic Kell blood group antigen.
This glycoprotein forms a disulfide bond with the XK membrane protein carrying the Kx antigen.
It shares sequence and structural similarity with neprilysin (M13) family zinc endopeptidases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.