Thermo Fisher Scientific TNFR2 Recombinant Rabbit Monoclonal Antibody (R204)
Thermo Fisher Scientific의 TNFR2 Recombinant Rabbit Monoclonal Antibody (R204)는 Mouse TNFR2/TNFRSF1B/CD120b에 특이적입니다. 높은 특이성과 재현성을 제공하며, 보존제가 없는 액상 형태로 제공됩니다. 중화 및 차단 분석에 적합하며, 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Neutralization (Neu) | 16–50 ng/mL | View 1 publication |
| Blocking Assay (BLOCK) | 0.2–0.7 µg/mL | - |
| In vitro Assay (IV) | – | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | R204 |
| Immunogen | Recombinant Mouse TNFR2/TNFRSF1B/CD120b protein (Met1–Gly258) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.64 mg/mL |
| Purification | Protein A |
| Storage Buffer | Histidine/arginine, pH 6, with 120 mM NaCl, 0.02% Tween 80 |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785656 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to avoid contamination.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody has specificity for Mouse TNFR2/TNFRSF1B/CD120b.
Target Information
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha and lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha.
The TRAF1/TRAF2 complex recruits apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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