Thermo Fisher Scientific RSV Fusion Protein Polyclonal Antibody
Rabbit polyclonal antibody targeting RSV Fusion Protein. Validated for Western blot and flow cytometry. High specificity and affinity purified by antigen chromatography. Suitable for research use in viral infection studies.
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- PA522824
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:2,000 |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Residues 201–211 [KELLPKVNNHDC] of the 63 kDa BRSV F protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157866 |
Target Information
Human respiratory syncytial virus (RSV) is a member of the Paramyxoviridae family, subfamily Pneumovirinae, that causes common respiratory tract infections such as measles and mumps.
Its genome consists of single-stranded, negative-sense RNA encoding three envelope glycoproteins: a small hydrophobic (SH) protein of unknown function, a major glycoprotein (G) known as the attachment protein, and a fusion (F) protein.
The 63 kDa RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, resulting in viral penetration, and can also fuse infected cells with neighboring cells, forming syncytia (multinucleated giant cells).
Its name derives from this fusion activity, as F proteins on the viral surface cause nearby cell membranes to merge.
While RSV typically produces mild symptoms in adults, it is a leading cause of lower respiratory tract infections and hospitalizations in infants and young children.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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