Thermo Fisher Scientific CD100 Polyclonal Antibody
인간 CD100(SEMA4D) 단백질에 특이적인 Rabbit Polyclonal 항체로, Western Blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 용액에 0.02% sodium azide를 포함하고 있습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Western Blot (WB): 1:100–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 777–788 of the human CD100 protein (SEMA4D, UniProt ID: Q92854-1). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152963 |
Product Specific Information
- Suggested positive control: antigen standard for SEMA4D (transient overexpression lysate).
Target Information
Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development.
CD100 (also known as semaphorin 4D), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro.
CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and downregulating CD23 expression.
CD72 is a lymphocyte receptor for the class IV semaphorin CD100, involved in regulating B cell signaling.
CD100 is expressed on resting and PHA-stimulated T cells, weakly on NK cells, EBV-transformed B cells, monocytes, and tumor/peripheral blood T cell lines, and at higher density on activated T and B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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