
ELK Biotechnology Ferritin heavy chain rabbit pAb
Ferritin heavy chain 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 철 저장 단백질 연구에 유용합니다. -20°C에서 장기 보관 가능합니다.
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Ferritin heavy chain rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | Ferritin heavy chain rabbit pAb |
| Alternative Names | FTH1; FTH; FTHL6; OK/SW-cl.84; PIG15; Ferritin heavy chain; Ferritin H subunit; Cell proliferation-inducing gene 15 protein |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the internal region of human Ferritin heavy chain |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 21 kDa |
| Gene ID (Human) | 2495 |
| Human Swiss-Prot No. | P02794 |
| Cellular Localization | Cell, nucleus, cytoplasm, mitochondrion, cytosol, intracellular ferritin complex, integral component of membrane, autolysosome, extracellular exosome |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. (provided by RefSeq, Jul 2008)
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