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ELK Biotechnology c-Fos (phospho Thr232) rabbit pAb
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c-Fos 단백질의 Thr232 인산화 부위를 인식하는 rabbit polyclonal antibody. WB, IHC, IF, ELISA에 사용 가능. 세포 성장 및 분화 연구에 적합. 사람, 생쥐, 랫트 시료에 반응. -20°C에서 1년 보관 가능.
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- pk
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ELK Biotechnology ES5351-100UL c-Fos (phospho Thr232) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES5351-50UL c-Fos (phospho Thr232) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology c-Fos (phospho Thr232) rabbit pAb
제품명
c-Fos (phospho Thr232) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | FOS; G0S7; Proto-oncogene c-Fos; Cellular oncogene fos; G0/G1 switch regulatory protein 7 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FOS around the phosphorylation site of Thr232 (AA range: 201–250). |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 62 kD |
| Gene ID (Human) | 2353 |
| Human Swiss-Prot No. | P01100 |
| Cellular Localization | Nucleus; Endoplasmic reticulum; Cytoplasm, cytosol. In quiescent cells, present in very small amounts in the cytosol. Following induction of cell growth, first localizes to the endoplasmic reticulum and later to the nucleus. Localization at the endoplasmic reticulum requires dephosphorylation at Tyr-10 and Tyr-30. |
| Species Reactivity | Human; Mouse; Rat |
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, forming the transcription factor complex AP-1. The FOS proteins act as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. (RefSeq, Jul 2008)
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