ELK Biotechnology HRT2 rabbit pAb
HRT2(HEY2) 단백질에 특이적인 rabbit polyclonal antibody로, WB, IHC, IF, ELISA 등 다양한 분석에 사용 가능. Notch 신호 경로 관련 전사 억제 인자 연구에 적합. 인간 및 생쥐 시료에 반응하며, 고농도(1 mg/ml) IgG 형태로 제공.
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제품명
HRT2 rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | HEY2; BHLHB32; CHF1; GRL; HERP; HERP1; HRT2; Hairy/enhancer-of-split related with YRPW motif protein 2; Cardiovascular helix-loop-helix factor 1; hCHF1; Class B basic helix-loop-helix protein 32; bHLHb32; HES-related repressor protein 2; Ha |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human HEY2 (AA range: 21–70) |
| Species Reactivity | Human; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 36 kD |
| GeneID (Human) | 23493 |
| Human Swiss-Prot No | Q9UBP5 |
| Cellular Localization | Nucleus |
| Storage | -20°C / 1 year |
| Host | Rabbit |
Background
This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. (RefSeq, Jul 2008)
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