ELK Biotechnology TCP-1 ε rabbit pAb
TCP-1 ε rabbit pAb는 CCT5 단백질을 인식하는 토끼 다클론 항체로, Western blot과 ELISA에 적합합니다. 세포질 내 단백질 접힘 복합체 연구에 활용되며, actin과 tubulin 등의 단백질 분석에 유용합니다. -20°C에서 1년 보관 가능합니다.
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TCP-1 ε rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | TCP-1 ε rabbit pAb |
| Alternative Names | CCT5; CCTE; KIAA0098; T-complex protein 1 subunit epsilon; TCP-1-epsilon; CCT-epsilon |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CCT5. AA range: 241-290 |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 67 kD |
| GeneID (Human) | 22948 |
| Human Swiss-Prot No | P48643 |
| Cellular Localization | Cytoplasm; cytoskeleton; microtubule organizing center; centrosome |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
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