ELK Biotechnology Factor XIII B rabbit pAb
Factor XIII B rabbit pAb는 인간, 랫, 마우스 시료에 반응하는 다클론 항체로 WB, IHC, IF, ELISA에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 1 mg/ml 농도와 80kD 밴드를 보입니다. 혈액 응고 인자 XIII B 서브유닛 연구에 유용합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology Factor XIII B rabbit pAb
Factor XIII B rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | Factor XIII B rabbit pAb |
| Alternative Names | F13B; Coagulation factor XIII B chain; Fibrin-stabilizing factor B subunit; Protein-glutamine gamma-glutamyltransferase B chain; Transglutaminase B chain |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human F13B (AA range: 61–110) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 80 kD |
| Gene ID (Human) | 2165 |
| Human Swiss-Prot No. | P05160 |
| Cellular Localization | Secreted |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of two A subunits and two B subunits. The A subunits have catalytic function, while the B subunits lack enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII consists only of two A subunits, identical to those of plasma origin. Upon activation by thrombin cleavage and in the presence of calcium ions, plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinks between fibrin molecules, stabilizing the fibrin clot. Factor XIII deficiency is associated with coagulation disorders.
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.