ELK Biotechnology ERβ (phospho Ser105) rabbit pAb

제품명

ERβ (phospho Ser105) rabbit pAb

제품 개요

ERβ (phospho Ser105) 항체는 인간 에스트로겐 수용체 베타의 Ser105 인산화 부위를 인식하는 토끼 폴리클로날 항체입니다. 핵, 세포질, 미토콘드리아에 존재하는 ERβ 단백질을 검출할 수 있으며, 다양한 연구 응용에 적합합니다.

제품 정보

Background

This gene encodes a member of the family of estrogen receptors and the superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA-binding domain and a C-terminal ligand-binding domain, and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17β-estradiol or related ligands, the encoded protein forms homo- or heterodimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, though the full-length nature of some variants has not been fully characterized. (RefSeq, Jul 2008)