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ELK Biotechnology ZnT-8 rabbit pAb
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ELK Biotechnology ZnT-8 rabbit pAb

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ZnT-8 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 인간, 쥐, 랫트 시료에서 반응하며 세포막 및 분비 소포막 단백질 검출에 활용됩니다. 인슐린 분비 관련 연구 및 당뇨병 관련 연구에 유용합니다.

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pk
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ELK Biotechnology ES4993-100UL ZnT-8 rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES4993-50UL ZnT-8 rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology ZnT-8 rabbit pAb

ELK Biotechnology ZnT-8 rabbit pAb

제품 정보

항목 내용
Product name ZnT-8 rabbit pAb
Alternative Names SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8
Applications WB; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
ELISA: 1/10000
Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human SLC30A8. AA range: 171–220
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 41 kD
GeneID (Human) 169026
Human Swiss-Prot No. Q8IWU4
Cellular Localization Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. Associated with insulin and glucagon secretory granules.
Species Reactivity Human; Rat; Mouse

Background

The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

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