ELK Biotechnology DD2 rabbit pAb
AKR1C2 단백질을 인식하는 토끼 다클론 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간 유래 합성 펩타이드로 면역화되었으며, 세포질 내 단백질 검출에 유용합니다. 고특이성과 안정적인 신호를 제공합니다.
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제품 개요
제품명: DD2 rabbit pAb
공급업체: ELK Biotechnology
제품 설명: AKR1C2 단백질을 인식하는 토끼 다클론 항체로, 다양한 면역학적 분석에 사용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | DD2 rabbit pAb |
| Alternative Names | AKR1C2; DDH2; Aldo-keto reductase family 1 member C2; 3-alpha-HSD3; Chlordecone reductase homolog HAKRD; Dihydrodiol dehydrogenase 2; DD-2; DD2; Dihydrodiol dehydrogenase/bile acid-binding protein; DD/BABP; Trans-1,2-dihydrobenzene-1,2-diol |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human AKR1C2 (AA range: 21–70) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 37 kDa |
| Gene ID (Human) | 1646 |
| Human Swiss-Prot No. | P52895 |
| Cellular Localization | Cytoplasm, cytosol |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. (RefSeq, Dec 2011)
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