Thermo Fisher Scientific Phospho-AS160 (Thr642) Polyclonal Antibody
AS160 단백질의 Thr642 인산화 부위를 인식하는 폴리클로날 항체로, Western blot 및 IHC에 적합. 인간과 생쥐에 반응하며, 항원 친화 크로마토그래피로 정제됨. 인슐린 매개 포도당 수송 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- View 12 publications
Immunohistochemistry (IHC)
- Tested Dilution: –
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human AS160 that contains threonine 642. The sequence is conserved in mouse. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.3, with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533564 |
Target Information
AS160 (TBC1D4) is a GTPase-activating protein for RAB2A, RAB8A, RAB10, and RAB14.
The isoform 2 version of this protein promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, increasing glucose uptake.
Mutations in this gene are associated with Diabetes mellitus, non-insulin-dependent, type 5 (NIDDM5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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