Thermo Fisher Scientific RAB3D Monoclonal Antibody (5E9), APC

Applications

• Western Blot (WB): 1:1,000

Product Specifications

Additional Formats

• FITC (Cat. No. MA5-45970)
• PerCP (Cat. No. MA5-45971)
• Custom conjugation available upon request

Product Specific Information

A 1:1,000 dilution of MA5-45969 was sufficient for detection of RAB3D in 10 µg of A549, T-47D cells, mouse and rat brain, and kidney by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody. Detects approximately 24 kDa. Does not show cross-reactivity to RAB3A, RAB3B, or RAB3C.

Target Information

Rab proteins are low-molecular-weight GTP-binding proteins belonging to the Ras superfamily of GTPases. They are localized on the cytoplasmic face of organelles and vesicles and are involved in intracellular membrane fusion reactions. Core fusion machinery includes SNAP-25, synaptobrevin, and syntaxin, which interact with NSF and α-SNAP. Rab proteins, with Munc-18, mediate vesicle docking and fusion. Over 40 Rab proteins have been described in mammals. Rab3D is expressed in tissues such as tongue, pancreas, and liver.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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