Thermo Fisher Scientific ARID1A Recombinant Rabbit Monoclonal Antibody (23GB3230)

Applications and Tested Dilutions

Product Specifications

Target Information

This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering chromatin structure.
The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin.
It possesses at least two conserved domains: a DNA-binding domain that binds AT-rich sequences and a C-terminal domain that stimulates glucocorticoid receptor-dependent transcriptional activation.
This protein may confer specificity to the SNF/SWI complex and recruit it to targets through protein-DNA or protein-protein interactions.
Two transcript variants encoding different isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.