Thermo Fisher Scientific nNOS Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:3000

-

Immunohistochemistry (IHC)

1:300-1:3000

-

Product Specifications

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptides from the c-terminal region of human NOS1 conjugated to an immunogenic carrier protein was used as the antigen. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:nNOS,uniProtId:P29475-1,ncbiNodeId:9606,antigenRange:1434,antigenLength:1434,antigenImageFileName:OSN00003W_nNOS_P29475-1_Goat.svg,antigenImageFileNamePDP:OSN00003W_nNOS_P29475-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10709560

Product Specific Information

Glycerol (1:1) may be added for additional stability.

Reconstitute with 150 µL of distilled water.

Target Information

NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM-dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.