
Thermo Fisher Scientific nNOS Polyclonal Antibody
Goat에서 유래한 nNOS 폴리클로날 항체로 Western Blot 및 Immunohistochemistry에 사용 가능. 인간 NOS1의 C-말단 합성 펩타이드로 면역화됨. 장기 보관 시 -20°C에서 안정적이며, 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:3000 |
| Immunohistochemistry (IHC) | 1:300–1:3000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptides from the C-terminal region of human NOS1 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10709560 |
Product Specific Information
- Glycerol (1:1) may be added for additional stability.
- Reconstitute with 150 µL of distilled water.
Target Information
NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH, and O₂) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin, and heme).
Several distinct NOS isoforms have been described and shown to represent the products of three distinct genes. These include two constitutive Ca²⁺/CaM-dependent forms of NOS:
- NOS1 (ncNOS): activity first identified in neurons
- NOS3 (ecNOS): activity first identified in endothelial cells
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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