Thermo Fisher Scientific CD4 Monoclonal Antibody (OX35), eBioscience
Rat CD4 단백질을 인식하는 OX35 단클론 항체로, Flow Cytometry 및 IHC(Frozen)에 적합합니다. 비결합형 액상 포맷이며, 0.5 mg/mL 농도로 제공됩니다. 고순도(>90%)로 SDS-PAGE 검증 완료, 4°C 보관. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 14-0040-xx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD4 Monoclonal Antibody (OX35), eBioscience
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent | - |
| Immunocytochemistry (ICC/IF) | - | 1 publication |
| Flow Cytometry (Flow) | 0.25 µg/test | 25 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Published Species | Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX35 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2864808 |
Additional Conjugate Formats
- APC (Cat. 17-0040-82)
- FITC (Cat. 11-0040-82)
- PE (Cat. 12-0040-82)
- PerCP-eFluor 710 (Cat. 46-0040-82)
- Super Bright 436 (Cat. 62-0040-82)
- Super Bright 600 (Cat. 63-0040-82)
- Super Bright 780 (Cat. 78-0040-82)
- Custom conjugation available upon request
Product Specific Information
Description:
The OX35 monoclonal antibody reacts with rat CD4. CD4 is a co-receptor involved in T cell receptor signaling via interaction with MHC class II on antigen-presenting cells (APCs). CD4 is expressed in thymus by CD4+CD8+ double-positive and CD4+ single-positive thymocytes, and by CD4+ helper T cells in peripheral tissues. CD4 is a membrane glycoprotein with four extracellular immunoglobulin-like domains.
Applications Reported:
This antibody is reported for use in flow cytometric analysis and immunohistology of frozen tissue sections.
Applications Tested:
Tested by flow cytometric analysis of rat splenocytes. Recommended usage ≤0.25 µg per test (100 µL volume). Optimal dilution should be determined empirically based on cell number (10⁵–10⁸ cells/test).
Purity: >90% (SDS-PAGE verified)
Aggregation: <10% (HPLC verified)
Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD4 antigen is a co-receptor for MHC class II recognition and HIV entry. It is mainly expressed in T helper lymphocytes, as well as monocytes, macrophages, and dendritic cells. CD4 expression is found in thymus, lymph nodes, tonsils, spleen, and various non-lymphoid tissues such as brain and gut. CD4 participates in early T-cell activation through association with the T-cell receptor complex and Lck kinase, and may mediate neuronal damage in immune-related CNS diseases. Multiple alternatively spliced transcripts have been reported (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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