Thermo Fisher Scientific MYBBP1A Polyclonal Antibody
MYBBP1A 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간 시료에 반응하며, 고순도 항원 친화 크로마토그래피 정제 제품입니다. 액상 형태로 -20°C에서 보관합니다.
- 카탈로그번호
- TA890056
- 판매단위
- pk
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human MYBBP1A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.19 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
The Myb family of transcription factors, including A-, B-, and c-Myb genes, regulate differentiation, cellular growth, and gene expression. c-Myb is crucial for hematopoietic cell proliferation and differentiation. Myb-binding protein 1A (MYBBP1A) is a nuclear protein localized mainly in nucleoli. Initially identified as a c-Myb-interacting protein, MYBBP1A is ubiquitously expressed and associates with various transcription factors. It interacts with the aromatic hydrocarbon receptor (AhR), enhancing AhR-dependent gene expression, and negatively regulates PPAR gamma coactivator 1 alpha (PGC-1α) via p38 MAPK. MYBBP1A also functions as a nucleocytoplasmic shuttling protein using CRM1-dependent and independent export pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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