Thermo Fisher Scientific CTR1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-Dependent

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:250

-

Immunohistochemistry (Frozen) (IHC (F))

Assay-Dependent

-

Immunocytochemistry (ICC/IF)

1:500

View 1 publication 1 publication

Product Specifications

Species Reactivity

Dog, Human, Mouse, Pig, Rat, Xenopus, Zebrafish

Published species

Zebrafish

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide of C-terminal region of human CTR1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CTR1,uniProtId:O15431-1,ncbiNodeId:9606,antigenRange:190,antigenLength:190,antigenImageFileName:PA1-16586_CTR1_O15431-1_Rabbit.svg,antigenImageFileNamePDP:PA1-16586_CTR1_O15431-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_568506

Product Specific Information

Suggested positive control: human breast cancer and kidney tissue.

Target Information

The trace metal copper (Cu) plays a crucial role in mammalian cells as a cofactor for many enzymes. Cu-related genetic diseases, such as Menkes disease and Wilson disease, arise from a lack of Cu homeostasis in mammalian cells. CTR1 is a high-affinity copper-uptake protein. The C-terminal domain is similar to the Raf family of protein kinases, but it`s first two-thirds encodes a novel protein domain. CTR1 provides the primary avenue for copper uptake in mammalian cells, thereby, affecting Cu homeostasis and embryonic development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.