Thermo Fisher Scientific CTR1 Polyclonal Antibody
CTR1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western Blot, IHC, ICC 등 다양한 응용에 사용 가능하며, 인간 및 여러 종에 반응합니다. 항원 친화 크로마토그래피로 정제된 액상 형태로, 구리 항상성 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-Dependent | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:250 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent | - |
| Immunocytochemistry (ICC/IF) | 1:500 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Pig, Rat, Xenopus, Zebrafish |
| Published Species | Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide of C-terminal region of human CTR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_568506 |
Product Specific Information
Suggested positive control: human breast cancer and kidney tissue.
Target Information
Copper (Cu) is a crucial trace metal acting as a cofactor for many mammalian enzymes. Genetic diseases such as Menkes and Wilson disease result from disrupted Cu homeostasis. CTR1 is a high-affinity copper-uptake protein; its C-terminal domain resembles the Raf family kinases, while the N-terminal region encodes a novel domain. CTR1 mediates copper uptake, influencing Cu homeostasis and embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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