Thermo Fisher Scientific Phospho-PBK (Thr9) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human PBK(Accession Q96KB5), corresponding to amino acid residues around phosphorylated Thr9. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PBK,uniProtId:Q96KB5-1,ncbiNodeId:9606,antigenRange:9,antigenLength:322,antigenImageFileName:PA5-104630_PBK_Q96KB5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-104630_PBK_Q96KB5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2816105

Product Specific Information

Antibody detects endogenous levels of PBK/TOPK only when phosphorylated at Thr9.

Target Information

PBK (TOPK) is a serine/threonine kinase that is related to the dual specific mitogen-activated protein kinase (MAPKK). The kinase is up-regulated in a variety of hematological malignancies, participates in activating lymphoid cells, and supports testicular function (spermatogenesis). Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.