Thermo Fisher Scientific Phospho-PBK (Thr9) Polyclonal Antibody
Phospho-PBK (Thr9) 폴리클로날 항체로 인간 및 마우스 PBK/TOPK 인산화 Thr9 부위를 특이적으로 검출. Western blot 및 IHC(P) 적용 가능. 고순도 정제, 1 mg/mL 농도, 안정적인 PBS/glycerol buffer에 보관. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PBK (Accession Q96KB5), corresponding to amino acid residues around phosphorylated Thr9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816105 |
Product Specific Information
Antibody detects endogenous levels of PBK/TOPK only when phosphorylated at Thr9.
Target Information
PBK (TOPK) is a serine/threonine kinase related to dual-specific mitogen-activated protein kinase (MAPKK). This kinase is up-regulated in various hematological malignancies, participates in lymphoid cell activation, and supports testicular function (spermatogenesis). Mitotic phosphorylation is required for its catalytic activity, suggesting a role in lymphoid activation and spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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