Thermo Fisher Scientific Cathepsin C/DPP1 Polyclonal Antibody
Cathepsin C/DPP1 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 1 mg/mL 농도, 연구용 전용 시약.
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Thermo Fisher Scientific Cathepsin C/DPP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human DPP-I, amino acids 365–463 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS (pH 7.4) with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cathepsin C, also known as dipeptidyl aminopeptidase I (DPPI), is a tetrameric lysosomal cysteine peptidase belonging to the papain family. It participates in intracellular protein degradation and processing of protein precursors, contributing to cell growth, neuraminidase activation, and platelet factor XIII activation. Cathepsin C is related to other lysosomal cysteine proteinases such as cathepsin B, H, and L. It sequentially removes dipeptides from the amino terminus and requires halide ions (chloride) and thiols for full enzymatic activity. Highly expressed in spleen, kidney, cytotoxic lymphocytes, and myeloid cells, Cathepsin C localizes to secretory granules and is synthesized as a proenzyme that is processed into two chains forming the mature enzyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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