Thermo Fisher Scientific C5b-9 Polyclonal Antibody
C5b-9 복합체를 인식하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 반응성. IHC, ICC/IF 등 다양한 면역염색에 적용 가능. 고순도 Protein A 정제, 안정적 액상 형태로 연구용 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: 1:100–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Purified Human SC5b-9 Complex |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The complement system is a fundamental part of innate immunity, consisting of over 45 genes that encode various complement components, regulators, and receptors.
The complement C5b-9 complex, also known as the Membrane Attack Complex (MAC), plays a crucial role in immune defense. It is composed of sequentially assembled proteins C5b, C6, C7, C8, and multiple copies of C9, forming transmembrane channels that puncture target cell membranes, leading to lysis.
MAC is involved not only in antimicrobial activity but also in inducing cell death in tumor cells, influencing cancer progression. The related genes are mainly organized in three major loci across the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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