Thermo Fisher Scientific Growth Hormone Polyclonal Antibody, FITC
FITC로 표지된 성장호르몬 폴리클로날 항체로, Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. 사람, 마우스, 랫트 반응성이 있으며, 친화 크로마토그래피로 정제되었습니다. -20°C에서 암소 보관하며 연구용으로만 사용 가능합니다.
- 카탈로그번호
- GH112-FITC
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | C-epitope synthetic peptide within amino acid region 150–250 on human Growth Hormone beta subunit protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones that play an important role in growth control. The GH1 gene, along with four additional related genes, is located at the growth hormone locus on chromosome 17. These five genes share a remarkably high degree of sequence identity. Alternative splicing results in five isoforms ranging from approximately 19 kDa to 24 kDa.
hGH is produced by somatotroph cells in the pituitary and acts through binding to membrane receptors of the cytokine receptor subfamily. Its major role in stimulating body growth is mediated by inducing the liver and other tissues to secrete IGF-1, promoting differentiation and proliferation of myoblasts, and enhancing amino acid uptake and protein synthesis in muscle and other tissues.
Mutations or deletions in the gene can lead to growth hormone deficiency and short stature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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