Thermo Fisher Scientific CD106 (VCAM-1) Monoclonal Antibody (STA), Alexa Fluor 488, eBioscience
인간 CD106(VCAM-1)을 인식하는 STA 클론 단일클론 항체로, Alexa Fluor 488 형광 표지. Flow Cytometry에 최적화된 사용 농도(5 µL/test). 염증 반응 관련 연구에 적합하며, 4°C 암조건 보관.
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제품 개요
제품명: CD106 (VCAM-1) Monoclonal Antibody (Clone STA), Alexa Fluor 488
공급업체: Thermo Fisher Scientific (eBioscience)
형태: Monoclonal Antibody, Alexa Fluor 488 Conjugate
용도: Flow Cytometry (FACS) 분석용
Applications
- Flow Cytometry (Flow): Tested at 5 µL (0.5 µg)/test
- Publications: View 5 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Alexa Fluor™ 488, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | STA |
| Conjugate | Alexa Fluor™ 488 |
| Excitation / Emission Max | 499 / 520 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802312 |
Additional Formats
Product Specific Information
The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to Integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1). Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.
Applications Reported: Flow cytometric analysis
Applications Tested: Pre-diluted and tested by flow cytometric analysis of stimulated HUVEC.
Recommended Use: 5 µL (0.5 µg) per test (100 µL final volume).
Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser
Target Information
VCAM-1 is a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. It regulates leukocyte migration, leukocyte-endothelial adhesion, and signal transduction, and may play a role in inflammatory disease mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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