Thermo Fisher Scientific GABBR2 Recombinant Rabbit Monoclonal Antibody (19H3L12)
GABBR2 단백질을 인식하는 재조합 토끼 단클론 항체로, IHC 및 ICC/IF에 1:500 희석 비율로 사용 가능. 인간 및 랫트 반응성 확인, 원숭이·마우스·개에서도 반응 예측. 높은 특이성과 민감도, 로트 간 일관성 및 동물유래 성분 없음.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 19H3L12 |
| Immunogen | Peptide corresponding to human GABBR2 (aa318–aa333) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2734809 |
Product Specific Information
This antibody is predicted to react with Monkey, Mouse, and Dog.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The specific antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
The multi-pass membrane protein GABBR2 belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily.
GABA-B receptors inhibit neuronal activity via G protein-coupled second-messenger systems that regulate neurotransmitter release and ion channel activity.
GABBR2 forms an active heterodimeric complex with GABA-B receptor subunit 1; neither is functional alone.
Allelic variants of this gene have been associated with nicotine dependence.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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