Thermo Fisher Scientific CREM Polyclonal Antibody
CREM 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ICC/IF, ELISA 등 다양한 응용 가능. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제, 안정적 PBS/glycerol 저장 buffer 구성.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human CREM (NP_853549.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.45 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2914502 |
Product Specific Information
- Positive test controls: 293T, K-562, Mouse testis, Rat testis
- Localization: Cytoplasm, Nucleus
Immunogen sequence:
MSKCARKKYI KTNPRQMTME TVESQHDGSI TASLTESKSA HVQTQTGQNS IPALAQVAAI AETDESAESE GVIDSHKRRE ILSRRPSYRK ILNELSSDVP
Target Information
CREM gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle and other complex processes. Alternative promoter and translation initiation site usage provide spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encode several isoforms, functioning as activators or repressors of transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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