Thermo Fisher Scientific Phospho-PTRF (Tyr156) Polyclonal Antibody
Human PTRF 단백질의 Tyr156 인산화 부위를 인식하는 rabbit polyclonal antibody. Western blot에 1:1,000~1:3,000 희석으로 사용 가능. 액상 형태, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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- PA5118781
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PTRF around the phosphorylation site of Tyr156 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903281 |
Target Information
The polymerase I and transcript release factor (PTRF) enables the dissociation of paused ternary polymerase I transcription complexes from the 3′ end of pre-rRNA transcripts, regulating rRNA transcription by promoting the dissociation of transcription complexes and the re-initiation of polymerase I on nascent rRNA transcripts. PTRF also localizes to caveolae at the plasma membrane and plays a critical role in caveolae formation and caveolin stabilization, translocating from caveolae to the cytoplasm after insulin stimulation. PTRF is also involved in lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in generalized lipodystrophy and muscular dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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