Thermo Fisher Scientific Mouse BMAL1 (aa 582-594) Synthetic Peptide

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

-

Product Specifications

Class

Synthetic

Type

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

PEP-075 is a 13 amino acid synthetic peptide whose sequence corresponds to residues 582-594 of mouse BMAL-1 with an amino terminal cysteine added for carrier protein conjugation. The sequence of this peptide is (amino to carboxy terminus): (C)-D582-M-I-D-N-D-Q-G-S-S-S-P-S594

This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and mouse BMAL-1, catalog # PA1-523. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.

Reconstitute with 0.1 mL of distilled water.

Target Information

The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.