Thermo Fisher Scientific Cadherin 17/LI Cadherin (Liver-Intestine Marker) Monoclonal Antibody (CDH17/2617)
인간 CDH17 단백질을 인식하는 마우스 단클론 항체로, 간 및 장 조직 마커 연구용에 적합합니다. Western blot, IHC, Peptide Array 등 다양한 응용에 사용 가능하며, 단백질 A로 정제된 액상형 제품입니다. 4°C 보관, 동결 금지.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | — |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | — |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL | — |
| Peptide Array (Array) | Assay-dependent | — |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CDH17/2617 |
| Immunogen | Recombinant fragment (around aa 242–418) of human Cadherin 17 (CDH17) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CDH17 gene belongs to the cadherin superfamily, which encodes calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, containing seven cadherin domains and a transmembrane region but lacking the conserved cytoplasmic domain. It is expressed in the gastrointestinal tract and pancreatic ducts, functioning as an intestinal proton-dependent peptide transporter involved in the absorption of peptide-based drugs. It may also play a role in the morphological organization of the liver and intestine. Multiple transcript variants exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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