Thermo Fisher Scientific IMPDH2 Recombinant Rabbit Monoclonal Antibody (JE40-87)
IMPDH2 단백질을 인식하는 토끼 유래 재조합 단클론 항체. Western blot, IHC, ICC, Flow cytometry, IP에 적합. 고순도 Protein A 정제 및 1 mg/mL 농도. 다양한 인체 조직에서 검증된 신뢰성 높은 연구용 항체.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:10–1:50 |
| Immunoprecipitation (IP) | 1:10–1:50 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE40-87 |
| Immunogen | Recombinant protein within Human IMPDH2 (aa 80–320) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848729 |
Product Specific Information
Positive Control:
Daudi, A431, LOVO, PC-3M, rat kidney tissue, human tonsil tissue, human thyroid gland tissue, mouse testis tissue.
Target Information
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis pathway. It maintains cellular guanine deoxy- and ribonucleotide pools required for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting a role in malignant transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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