Thermo Fisher Scientific IMPDH2 Recombinant Rabbit Monoclonal Antibody (JE40-87)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

Flow Cytometry (Flow)

1:10-1:50

-

Immunoprecipitation (IP)

1:10-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

JE40-87

Immunogen

Recombinant protein within Human IMPDH2 aa 80-320 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IMPDH2,uniProtId:P12268-1,ncbiNodeId:9606,antigenRange:80-320,antigenLength:514,antigenImageFileName:MA5-34821_IMPDH2_P12268-1_Rabbit.svg,antigenImageFileNamePDP:MA5-34821_IMPDH2_P12268-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 40% glycerol, 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles, store in dark

Shipping conditions

Wet ice

RRID

AB_2848729

Product Specific Information

Positive Control: Daudi, A431, LOVO, PC-3M, rat kidney tissue, human tonsil tissue, human thyroid gland tissue, mouse testis tissue.

Target Information

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5-monophosphate into xanthine-5-monophosphate, which is then converted into guanosine-5`-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.