Thermo Fisher Scientific Alpha-Smooth Muscle Actin Monoclonal Antibody (1A4), Alexa Fluor 700
Alpha-Smooth Muscle Actin(α-SMA)을 인식하는 1A4 단클론 항체로, Alexa Fluor 700으로 표지되어 있습니다. 사람, 마우스, 랫트 시료에 반응하며 IHC(P)에서 1 µg/mL로 사용 가능합니다. 평활근세포 및 근섬유모세포 표지에 유용하며 연구용으로만 사용됩니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A4 |
| Conjugate | Alexa Fluor™ 700 |
| Excitation / Emission Max | 696 / 719 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.5% BSA, 10% proprietary stabilizer |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Wet ice |
Additional Formats
- Unconjugated (Cat. MA1-06110)
- Alexa Fluor 420 (Cat. 758-9760-82)
- Alexa Fluor 514 (Cat. 753-9760-82)
- Alexa Fluor Plus 594 (Cat. 755-9760-82)
- Alexa Fluor Plus 750 (Cat. 757-9760-82)
- Custom conjugation available upon request
Product Specific Information
The monoclonal antibody 1A4 recognizes human, mouse, and rat alpha-smooth muscle actin (α-SMA), a 42 kDa protein that is a major component of the cytoskeletal structural network. This antibody specifically detects the alpha form of muscle actin expressed by smooth muscle cells of blood vessels, myofibroblasts, and myoepithelial cells. It is also found in the parenchyma and stroma of various tissues.
Alpha-smooth muscle actin is useful for identifying leiomyomas, leiomyosarcomas, and pleomorphic adenomas and serves as a prognostic marker for basal cell carcinoma.
Applications Reported:
- Immunohistochemical staining of formalin-fixed paraffin-embedded tissue sections
- Immunocytochemistry
Applications Tested:
This antibody has been validated for IHC using high pH antigen retrieval and can be used at 1 µg/mL. Optimal dilution should be determined experimentally.
Handling Note:
Centrifuge the conjugate solution briefly before use and use only the supernatant to minimize nonspecific background caused by aggregates.
Target Information
Smooth Muscle Actin belongs to the actin family of highly conserved proteins involved in cell motility, structure, and integrity. Alpha actin is a major component of the contractile apparatus, while beta and gamma actins regulate cell motility.
Smooth muscle actin is abundant in vascular and visceral smooth muscle cells and is also observed in fibroblastic stress fibers during wound healing and fibrocontractive diseases.
Defects in the smooth muscle actin gene are associated with familial thoracic aortic aneurysm type 6. Multiple alternatively spliced variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific RPMI 1640 Medium, GlutaMAX Supplement, 500 mL
65,500원
Thermo Fisher Scientific
Thermo Fisher Scientific Mouse EGF Native Protein
552,300원
Thermo Fisher Scientific
Thermo Fisher Scientific Alpha-Smooth Muscle Actin Monoclonal Antibody (1A4), Alexa Fluor 700
818,200원
Thermo Fisher Scientific
Thermo Fisher Scientific PBS (10X), pH 7.4, 500 mL
79,200원
Thermo Fisher Scientific
Thermo Fisher Scientific PBS (10X), pH 7.2, 500 mL
81,200원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|