Thermo Fisher Scientific BRG1/SMARCA4 Recombinant Rabbit Monoclonal Antibody (BRG1/7633R)
BRG1/SMARCA4 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot, IHC, ELISA 등 다양한 응용에 적합. 높은 특이성과 재현성을 제공하며, 연구용으로 사용 가능. PBS 용액 형태로 -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BRG1/7633R |
| Immunogen | Recombinant fragment (around aa 200–400) of human SMARCA4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair, and DNA replication.
Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cell differentiation, neurogenesis, and cell cycle regulation.
Brg1 is essential for mouse embryogenesis and is involved in cell growth arrest, senescence, and tumor suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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