Thermo Fisher Scientific PABPC1 Polyclonal Antibody
Thermo Fisher Scientific의 PABPC1 Polyclonal Antibody는 인간 PABPC1 단백질을 인식하는 토끼 유래 폴리클로날 항체입니다. Western blot 및 ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA566900
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PABP. Recombinant protein control fragment (Product #RP-105419) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662551 |
Product Specific Information
Immunogen sequence:QTQNRAAYYPP SQIAQLRPSP RWTAQG
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
PABPC1b encodes a poly(A) binding protein.
The protein shuttles between the nucleus and cytoplasm and binds to the 3′ poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs.
Binding of this protein to poly(A) promotes ribosome recruitment and translation initiation and is required for poly(A) shortening, the first step in mRNA decay.
The gene is part of a small gene family including three protein-coding genes and several pseudogenes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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