Thermo Fisher Scientific PRMT5 Monoclonal Antibody (OTI4G7), TrueMAB

Applications

Western Blot (WB)

• Assay-dependent

Immunohistochemistry (Paraffin) (IHC (P))

• Dilution: 1:150

Product Specifications

Product Specific Information

• For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of ~1 mg/mL.
• For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

PRMT5 (Protein Arginine N-Methyltransferase 5) is an arginine methyltransferase that catalyzes the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for MMA formation.
PRMT5 mediates symmetrical dimethylation of arginine residues in small nuclear ribonucleoproteins Sm D1 and Sm D3, which is essential for snRNP core particle assembly and biogenesis.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.